JWH-081, also known as N-(4-hydroxypentyl) metabolite, is a synthetic cannabinoid that acts as a potent agonist at the cannabinoid receptors in the human body. It is a metabolite of JWH-081, which is a designer drug that belongs to the family of synthetic cannabinoids. This specific metabolite is formed when the parent compound, JWH-081, undergoes biotransformation in the body's metabolic processes. The hydroxyl group added to the pentyl side chain enhances its potency and affinity for the cannabinoid receptors, leading to increased psychoactive effects.
The cannabinoid receptors are distributed throughout the central nervous system and play a crucial role in modulating various physiological processes such as pain perception, appetite regulation, mood, and cognition. By binding to these receptors, JWH-081 and its metabolite can elicit similar effects to those produced by the natural compounds found in cannabis, such as THC. However, it is important to note that JWH-081 and its metabolite are not approved for medical use and are considered illegal in many jurisdictions due to their potential for abuse and adverse health effects. Furthermore, the long-term consequences of using synthetic cannabinoids are still relatively unknown, making their use highly risky.
Below are some of the side effects of JWH-081
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